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What is Psilocybin?

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Psilocybin is the naturally occurring psychedelic compound found in over 200 species of “magic mushrooms.” Once ingested, the body converts psilocybin into psilocin, which binds to serotonin receptors in the brain and produces about four to six hours of altered consciousness that can include enhanced emotions, sensory changes, and meaningful personal insights. Although long used in traditional healing ceremonies, psilocybin is now being researched under carefully controlled conditions for potential benefits in depression, anxiety, addiction, and cancer-related distress (including CAN-PACT!).

What are Other Commonly Asked Questions?

What is a ‘Psychedelic’?

A psychedelic is a type of psycho-active substance that temporarily alters perception, mood, and thinking in ways that can include vivid sensory changes (such as brighter colours or unusual patterns), new emotional insights, and a sense of connection to people, nature, or spirituality. Classic psychedelics (e.g., psilocybin, LSD, DMT, mescaline) primarily work by stimulating the brain’s 5-HT2A serotonin receptors, which helps explain their distinctive mind-expanding effects.

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What is ‘Psychedelic-Assisted Therapy (PAT)’?

Psychedelic-assisted therapy combines one or a few supervised doses of a psychedelic agent (such as psilocybin) with structured therapy before, during, and after the dosing session. In a safe, supportive setting, trained therapists prepare participants, guide them through the altered-state experience, and help them integrate insights into daily life. Early research suggests this approach may offer rapid and long-lasting relief for conditions like depression, post-traumatic stress, substance use disorders, and existential distress in serious illness.

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What is ‘Mindfulness’?

Mindfulness is the practice of paying purposeful, non-judgmental attention to one’s present-moment experience - thoughts, emotions, body sensations, and surroundings - exactly as they are. Cultivated through meditation, gentle movement, or everyday activities, mindfulness helps people notice automatic reactions, reduce stress, and relate to themselves and others with greater openness, curiosity, and compassion.

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